Most mods in Vault Hunters are locked behind Research. The player can find Knowledge Essence inside living chests and craft Knowledge Stars with some Vault Diamonds and Benitoite.
Knowledge Crafting
Item
Crafting Recipe
Knowledge Star Shard
Knowledge Core
Knowledge Star
After right clicking a Knowledge Star in the air the player receive one unspent knowledge point. Those points can be spent inside the Research tab.
Research Groups
Storage
Colossal Chest
Colossal Chest allows you to build massive chests that can store a lot of items in them.
Simple Storage Network
Simple Storage Network is a mod that lets you connect up several inventories and browse their content.
Drawers
This mod can multiple stacks of one item in one block.
Mekanism QIO
Storage System of the mekanism mod.
Refined Storage
Description
Applied Energistics
Description
Looting
Stack Upgrading
Stack Upgrades increases the amount of items that can be stored in a single slot.
Auto Refill
Refill Upgrades can automatically refill your hotbar with your selected blocks and/or items.
Auto Feeding
Feeding Upgraded can automatically feed you directly from your pouches, belts & backpacks and removes the need to eat food manually.
Double Pouches
Unlocks the ability to craft Double Pouches, which offers more storage space and one more upgrade slot than Pouches.
Belts
Unlocks the ability to craft Belts, which offers more storage space than Double Pouches.
Backpacks
Unlocks the ability to craft Backpacks, which offers more storage space and two more upgrade slots than Belts.
Big Backpacks
Unlocks the ability to craft Big Backpacks, which offers more storage space and two more upgrade slots than Backpacks.
Soul Harvester
Unlocks the Soul Harvester which is a much faster way to breaking down items to Soul Essence.
Junk Management
Unlocks the Void Crucible and the ability to void items inside the vault.